A simple, one-pot high frequency ultrasonication (490 kHz) methodology to convert hydrophobic and amphipathic amino acids into nanostructures was investigated. The approach involved the oxidative coupling of aromatic amino acids (phenylalanine and tryptophan) in aqueous solutions to form high molecular weight dimers and oligomers. The role of cavitation bubble surface and ultrasonic power to trigger the out-of-equilibrium self-assembly of dimers and trimers to spherical and uniform nanostructures with controlled size has been discussed. The synthesized particles exhibited fluorescence in blue, green and red spectral regions and a strong antioxidant activity.
Bhangu, S.k., Ashokkumar, M., Cavalieri, F. (2020). Synthesis of bio-functional nanoparticles from sono-responsive amino acids using high frequency ultrasound. ULTRASONICS SONOCHEMISTRY, 63, 104967 [10.1016/j.ultsonch.2020.104967].
Synthesis of bio-functional nanoparticles from sono-responsive amino acids using high frequency ultrasound
Cavalieri, Francesca
2020-05-01
Abstract
A simple, one-pot high frequency ultrasonication (490 kHz) methodology to convert hydrophobic and amphipathic amino acids into nanostructures was investigated. The approach involved the oxidative coupling of aromatic amino acids (phenylalanine and tryptophan) in aqueous solutions to form high molecular weight dimers and oligomers. The role of cavitation bubble surface and ultrasonic power to trigger the out-of-equilibrium self-assembly of dimers and trimers to spherical and uniform nanostructures with controlled size has been discussed. The synthesized particles exhibited fluorescence in blue, green and red spectral regions and a strong antioxidant activity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
