The synthetic drug fenoldopam mesylate (FM) may have a renoprotective role, and a "renal dose" of 0.1 µg/kg/min intravenous (IV) infusion of FM has been reported as able to increase renal blood flow without affecting systemic blood pressure. But conclusive data are still lacking. We aimed to investigate by color-Doppler ultrasonography the effects of IV administration of FM at this dosage in hypertensive chronic kidney disease (CKD) patients, and verify whether it may induce any systemic hemodynamic alteration.

Rovella, V., Ferrannini, M., Tesauro, M., Marrone, G., Busca, A., Sorge, R., et al. (2019). Effects of fenoldopam on renal blood flow in hypertensive chronic kidney disease. JN. JOURNAL OF NEPHROLOGY, 32(1), 75-81 [10.1007/s40620-018-0496-0].

Effects of fenoldopam on renal blood flow in hypertensive chronic kidney disease

Rovella V.;Tesauro M.;Sorge R.;Manca di Villahermosa S.;Di Daniele N.;Noce A.
2019-01-01

Abstract

The synthetic drug fenoldopam mesylate (FM) may have a renoprotective role, and a "renal dose" of 0.1 µg/kg/min intravenous (IV) infusion of FM has been reported as able to increase renal blood flow without affecting systemic blood pressure. But conclusive data are still lacking. We aimed to investigate by color-Doppler ultrasonography the effects of IV administration of FM at this dosage in hypertensive chronic kidney disease (CKD) patients, and verify whether it may induce any systemic hemodynamic alteration.
2019
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/09 - MEDICINA INTERNA
English
Arterial hypertension; Chronic kidney disease; Fenoldopam mesylate; Renal blood flow; Renal resistive index
Rovella, V., Ferrannini, M., Tesauro, M., Marrone, G., Busca, A., Sorge, R., et al. (2019). Effects of fenoldopam on renal blood flow in hypertensive chronic kidney disease. JN. JOURNAL OF NEPHROLOGY, 32(1), 75-81 [10.1007/s40620-018-0496-0].
Rovella, V; Ferrannini, M; Tesauro, M; Marrone, G; Busca, A; Sorge, R; Manca di Villahermosa, S; Casasco, M; Di Daniele, N; Noce, A
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/246263
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