Nitrobindins (Nbs) are evolutionary conserved all-β-barrel heme-proteins displaying a highly solvent-exposed heme-Fe(III) atom. The physiological role(s) of Nbs is almost unknown. Here, the structural and functional properties of the Mycobacterium tuberculosis Nb (Mt-Nb(III)) and Homo sapiens Nb (Hs-Nb(III)) have been investigated and compared with those of Arabidopsis thaliana Nb (At-Nb(III), of the hematophagous bug Rodius prolixus nitrophorins (Rp-NP(III)s), and of mammalian myoglobins.

De Simone, G., di Masi, A., Vita, G.m., Polticelli, F., Pesce, A., Nardini, M., et al. (2020). Mycobacterial and human nitrobindins: structure and function. ANTIOXIDANTS & REDOX SIGNALING, 33(4), 229-246 [10.1089/ars.2019.7874].

Mycobacterial and human nitrobindins: structure and function

Ciaccio, Chiara;Coletta, Massimiliano;
2020-01-01

Abstract

Nitrobindins (Nbs) are evolutionary conserved all-β-barrel heme-proteins displaying a highly solvent-exposed heme-Fe(III) atom. The physiological role(s) of Nbs is almost unknown. Here, the structural and functional properties of the Mycobacterium tuberculosis Nb (Mt-Nb(III)) and Homo sapiens Nb (Hs-Nb(III)) have been investigated and compared with those of Arabidopsis thaliana Nb (At-Nb(III), of the hematophagous bug Rodius prolixus nitrophorins (Rp-NP(III)s), and of mammalian myoglobins.
2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/10 - BIOCHIMICA
English
Con Impact Factor ISI
De Simone, G., di Masi, A., Vita, G.m., Polticelli, F., Pesce, A., Nardini, M., et al. (2020). Mycobacterial and human nitrobindins: structure and function. ANTIOXIDANTS & REDOX SIGNALING, 33(4), 229-246 [10.1089/ars.2019.7874].
De Simone, G; di Masi, A; Vita, Gm; Polticelli, F; Pesce, A; Nardini, M; Bolognesi, M; Ciaccio, C; Coletta, M; Turilli, Es; Fasano, M; Tognaccini, L; Smulevich, G; Abbruzzetti, S; Viappiani, C; Bruno, S; Ascenzi, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/245873
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