We have analysed the results of surgical treatment for microcarcinoma of the thyroid (MCT). In sixteen patient clinical and follow-up data were retrospectively evaluated during a 35.1-month follow-up. Thyroid hyperfunctional state us was present in two subjects. A single nodule was detected by echotomography in 11 patients, while multinodular diffuse goitre was revealed in 3 patients. In the last two subjects, thyroid gland appeared completely normal at ultrasonography, despite laterocervical lymph node metastases. Fine-needle aspiration biopsy was performed in 6 patients and its diagnostic accuracy was high (83,3%). MCT was classified as "incidental" in 12 patients and "occult" in the remaining 4 patients. Eight subjects underwent total thyroidectomy and 8 hemithyroidectomy plus isthmectomy. No postoperative complications were recorded. In 10 patients MCT histotype was papillar adenocarcinoma, in 5 was follicular adenocarcinoma and in the remaining case it was medullary carcinoma. Goitre was associated in 75% of the cases. Only in a patient disease progressed to death because of hematogenous metastases. In conclusion, we believe that incidental MCT is a low-grade malignancy with a benign biological behaviour. Occult MCT is a potentially lethal disease. We did not observe differences in the long-term results between different surgical treatments of MCT.

Russo, F., Barone Adesi, T.l., Arturi, A., Stolfi, V.m., Spina, C., Savio, A., et al. (1997). [Clinico-pathological study of microcarcinoma of the thyroid]. MINERVA CHIRURGICA, 52(7-8), 891-900.

[Clinico-pathological study of microcarcinoma of the thyroid]

Arturi, A;Stolfi, V M;Spina, C;De Majo, A;Uccioli, L;Gentileschi, P
1997

Abstract

We have analysed the results of surgical treatment for microcarcinoma of the thyroid (MCT). In sixteen patient clinical and follow-up data were retrospectively evaluated during a 35.1-month follow-up. Thyroid hyperfunctional state us was present in two subjects. A single nodule was detected by echotomography in 11 patients, while multinodular diffuse goitre was revealed in 3 patients. In the last two subjects, thyroid gland appeared completely normal at ultrasonography, despite laterocervical lymph node metastases. Fine-needle aspiration biopsy was performed in 6 patients and its diagnostic accuracy was high (83,3%). MCT was classified as "incidental" in 12 patients and "occult" in the remaining 4 patients. Eight subjects underwent total thyroidectomy and 8 hemithyroidectomy plus isthmectomy. No postoperative complications were recorded. In 10 patients MCT histotype was papillar adenocarcinoma, in 5 was follicular adenocarcinoma and in the remaining case it was medullary carcinoma. Goitre was associated in 75% of the cases. Only in a patient disease progressed to death because of hematogenous metastases. In conclusion, we believe that incidental MCT is a low-grade malignancy with a benign biological behaviour. Occult MCT is a potentially lethal disease. We did not observe differences in the long-term results between different surgical treatments of MCT.
Pubblicato
Rilevanza internazionale
Recensione
Esperti anonimi
Settore MED/18
English
Italian
Con Impact Factor ISI
Adenocarcinoma, Follicular; Adenocarcinoma, Papillary; Adult; Aged; Biopsy, Needle; Bone Neoplasms; Carcinoma, Medullary; Diagnosis, Differential; Female; Follow-Up Studies; Goiter, Nodular; Humans; Lymphatic Metastasis; Male; Middle Aged; Radionuclide Imaging; Retrospective Studies; Thyroid Gland; Thyroid Neoplasms; Time Factors
Russo, F., Barone Adesi, T.l., Arturi, A., Stolfi, V.m., Spina, C., Savio, A., et al. (1997). [Clinico-pathological study of microcarcinoma of the thyroid]. MINERVA CHIRURGICA, 52(7-8), 891-900.
Russo, F; Barone Adesi, Tl; Arturi, A; Stolfi, Vm; Spina, C; Savio, A; De Majo, A; Uccioli, L; Gentileschi, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/243355
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