The approval of Sativex for the management of multiple sclerosis (MS) spasticity opened a new opportunity to many patients. In Italy, the healthcare payer can be fully reimbursed by the involved pharma company with the cost of treatment for patients not responding after a 4 week (28 days) trial period (Payment by Results, PbR), and 50% reimbursed with the cost of 6 weeks (42 days) treatment for other patients discontinuing (Cost Sharing, CS). The aim of our study was to describe the Sativex discontinuation profile from a large population of spasticity treated Italian MS patients.

Messina, S., Solaro, C., Righini, I., Bergamaschi, R., Bonavita, S., Bossio, R.b., et al. (2017). Sativex in resistant multiple sclerosis spasticity: Discontinuation study in a large population of Italian patients (SA.FE. study). PLOS ONE, 12(8), e0180651 [10.1371/journal.pone.0180651].

Sativex in resistant multiple sclerosis spasticity: Discontinuation study in a large population of Italian patients (SA.FE. study)

Centonze D.
;
2017-08-01

Abstract

The approval of Sativex for the management of multiple sclerosis (MS) spasticity opened a new opportunity to many patients. In Italy, the healthcare payer can be fully reimbursed by the involved pharma company with the cost of treatment for patients not responding after a 4 week (28 days) trial period (Payment by Results, PbR), and 50% reimbursed with the cost of 6 weeks (42 days) treatment for other patients discontinuing (Cost Sharing, CS). The aim of our study was to describe the Sativex discontinuation profile from a large population of spasticity treated Italian MS patients.
1-ago-2017
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Adult; Aged; Aged, 80 and over; Cannabidiol; Cost Sharing; Dronabinol; Drug Approval; Drug Combinations; Drug Costs; Drug Industry; Female; Humans; Italy; Kaplan-Meier Estimate; Male; Middle Aged; Multiple Sclerosis; Multivariate Analysis; Muscle Spasticity; Parasympatholytics; Plant Extracts; Proportional Hazards Models; Registries; Regression Analysis; Severity of Illness Index; Young Adult
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180651
Messina, S., Solaro, C., Righini, I., Bergamaschi, R., Bonavita, S., Bossio, R.b., et al. (2017). Sativex in resistant multiple sclerosis spasticity: Discontinuation study in a large population of Italian patients (SA.FE. study). PLOS ONE, 12(8), e0180651 [10.1371/journal.pone.0180651].
Messina, S; Solaro, C; Righini, I; Bergamaschi, R; Bonavita, S; Bossio, Rb; Morra, Vb; Costantino, G; Cavalla, P; Centonze, D; Comi, G; Cottone, S; Danni, Mc; Francia, A; Gajofatto, A; Gasperini, C; Zaffaroni, M; Petrucci, L; Signoriello, E; Maniscalco, Gt; Spinicci, G; Matta, M; Mirabella, M; Peda, G; Castelli, L; Rovaris, M; Sessa, E; Spitaleri, D; Paolicelli, D; Granata, A; Zappia, M; Patti, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/241269
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