Although the number of disease-modifying treatments for people with multiple sclerosis (pwMS) has meaningfully increased in the past years, targeting repair or compensation for central nervous system damage associated with the disease process remains an important clinical goal. With this aim, neurorehabilitation is a powerful approach targeting central nervous system plasticity. Another driver of brain plasticity is non-invasive brain stimulation (NIBS), receiving recent attention in neurology, particularly for its potential synergy with neurorehabilitation and as add-on treatment for several neurological conditions, from pain to fatigue to sensorimotor and cognitive deficits. In this review, we will resume the evidence exploring the neurobiological basis of NIBS and its applications to MS-related conditions.

Leocani, L., Chieffo, R., Gentile, A., & Centonze, D. (2019). Beyond rehabilitation in MS: Insights from non-invasive brain stimulation. MULTIPLE SCLEROSIS, 25(10), 1363-1371 [10.1177/1352458519865734].

Beyond rehabilitation in MS: Insights from non-invasive brain stimulation

Gentile A.;Centonze D.
2019

Abstract

Although the number of disease-modifying treatments for people with multiple sclerosis (pwMS) has meaningfully increased in the past years, targeting repair or compensation for central nervous system damage associated with the disease process remains an important clinical goal. With this aim, neurorehabilitation is a powerful approach targeting central nervous system plasticity. Another driver of brain plasticity is non-invasive brain stimulation (NIBS), receiving recent attention in neurology, particularly for its potential synergy with neurorehabilitation and as add-on treatment for several neurological conditions, from pain to fatigue to sensorimotor and cognitive deficits. In this review, we will resume the evidence exploring the neurobiological basis of NIBS and its applications to MS-related conditions.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26
eng
Con Impact Factor ISI
Synaptic plasticity; experimental autoimmune encephalomyelitis (EAE); neuromodulation; transcranial direct current stimulation; transcranial magnetic stimulation
https://journals.sagepub.com/doi/full/10.1177/1352458519865734?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed
Leocani, L., Chieffo, R., Gentile, A., & Centonze, D. (2019). Beyond rehabilitation in MS: Insights from non-invasive brain stimulation. MULTIPLE SCLEROSIS, 25(10), 1363-1371 [10.1177/1352458519865734].
Leocani, L; Chieffo, R; Gentile, A; Centonze, D
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/239552
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