Alzheimer's disease (AD) is the most common form of dementia. It is mainly characterized by a progressive deterioration of cognition, but sleep-wake cycle disturbances frequently occur. Irregular sleep-wake cycle, insomnia, and daytime napping usually occur in patients with AD in the course of the disease.

Liguori, C., Spanetta, M., Izzi, F., Franchini, F., Nuccetelli, M., Sancesario, G.m., et al. (2020). Sleep-Wake Cycle in Alzheimer's Disease Is Associated with Tau Pathology and Orexin Dysregulation. JOURNAL OF ALZHEIMER'S DISEASE, 74(2), 501-508 [10.3233/JAD-191124].

Sleep-Wake Cycle in Alzheimer's Disease Is Associated with Tau Pathology and Orexin Dysregulation

Liguori, Claudio;Izzi, Francesca;Franchini, Flaminia;Di Santo, Simona;Bernardini, Sergio;Mercuri, Nicola Biagio;Placidi, Fabio
2020-02-10

Abstract

Alzheimer's disease (AD) is the most common form of dementia. It is mainly characterized by a progressive deterioration of cognition, but sleep-wake cycle disturbances frequently occur. Irregular sleep-wake cycle, insomnia, and daytime napping usually occur in patients with AD in the course of the disease.
10-feb-2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA
English
Alzheimer’s disease; cognition; orexin; sleep-wake cycle; tau proteins
Liguori, C., Spanetta, M., Izzi, F., Franchini, F., Nuccetelli, M., Sancesario, G.m., et al. (2020). Sleep-Wake Cycle in Alzheimer's Disease Is Associated with Tau Pathology and Orexin Dysregulation. JOURNAL OF ALZHEIMER'S DISEASE, 74(2), 501-508 [10.3233/JAD-191124].
Liguori, C; Spanetta, M; Izzi, F; Franchini, F; Nuccetelli, M; Sancesario, Gm; Di Santo, S; Bernardini, S; Mercuri, Nb; Placidi, F
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
liguori2020.pdf

solo utenti autorizzati

Tipologia: Versione Editoriale (PDF)
Licenza: Copyright dell'editore
Dimensione 81.05 kB
Formato Adobe PDF
81.05 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/237749
Citazioni
  • ???jsp.display-item.citation.pmc??? 21
  • Scopus 55
  • ???jsp.display-item.citation.isi??? 52
social impact