Doravirine, a novel NNRTI, selects for specific mutations in vitro, including mutations at reverse transcriptase (RT) positions 106, 108, 188, 227, 230 and 234. The aim of this study was to examine the prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients.

Soulie, C., Santoro, M.m., Storto, A., Abdi, B., Charpentier, C., Armenia, D., et al. (2020). Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY [10.1093/jac/dkz553].

Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy

Santoro, Maria Mercedes;Andreoni, Massimo;Perno, Carlo Federico;Ceccherini-Silberstein, Francesca;
2020-01-24

Abstract

Doravirine, a novel NNRTI, selects for specific mutations in vitro, including mutations at reverse transcriptase (RT) positions 106, 108, 188, 227, 230 and 234. The aim of this study was to examine the prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients.
24-gen-2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/17 - MALATTIE INFETTIVE
English
Soulie, C., Santoro, M.m., Storto, A., Abdi, B., Charpentier, C., Armenia, D., et al. (2020). Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY [10.1093/jac/dkz553].
Soulie, C; Santoro, Mm; Storto, A; Abdi, B; Charpentier, C; Armenia, D; Jary, A; Forbici, F; Bertoli, A; Gennari, W; Andreoni, M; Mussini, C; Antinori...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/233895
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