Herpes zoster (HZ; shingles)--a reactivation of the latent varicella zoster virus (VZV)--can cause significant morbidity. Its major complication is pain, particularly post-herpetic neuralgia (PHN). We will review the current management strategies available for the treatment of both acute HZ and PHN, including antiviral drugs, analgesic agents, anticonvulsants, tricyclic antidepressants and topical therapies. New molecules in development that show improved activity against VZV are also covered, and new drug targets are outlined. The role of translational neuroscience in moving towards a goal of finding disease-modifying treatments will be examined.
Whitley, R.J., Volpi, A., McKendrick, M., Wijck, A.v., & Oaklander, A.L. (2010). Management of herpes zoster and post-herpetic neuralgia now and in the future. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 48 Suppl 1, S20-8.
Tipologia: | Articolo su rivista |
Citazione: | Whitley, R.J., Volpi, A., McKendrick, M., Wijck, A.v., & Oaklander, A.L. (2010). Management of herpes zoster and post-herpetic neuralgia now and in the future. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 48 Suppl 1, S20-8. |
IF: | Con Impact Factor ISI |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore MED/17 - Malattie Infettive |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S1386-6532(10)70005-6 |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | mag-2010 |
Titolo: | Management of herpes zoster and post-herpetic neuralgia now and in the future |
Autori: | |
Autori: | Whitley, RJ; Volpi, A; McKendrick, M; Wijck, Av; Oaklander, AL |
Appare nelle tipologie: | 01 - Articolo su rivista |
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