Assays to estimate human immunodeficiency virus (HIV) reservoir size require large amounts of blood, which represents a drawback especially in pediatric settings. We investigated whether HIV-antibody repertoire could estimate the viral reservoir size. Moreover, we assessed the magnitude of HIV-antibody response as a predictor of time of antiretroviral therapy (ART) initiation.
Rocca, S., Zangari, P., Cotugno, N., De Rossi, A., Ferns, B., Petricone, D., et al. (2019). Human Immunodeficiency Virus (HIV)-Antibody repertoire estimates reservoir size and time of antiretroviral therapy initiation in virally suppressed perinatally HIV-infected children. JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 8(5), 433-438 [10.1093/jpids/piy080].
Human Immunodeficiency Virus (HIV)-Antibody repertoire estimates reservoir size and time of antiretroviral therapy initiation in virally suppressed perinatally HIV-infected children
Cotugno N.Investigation
;Petricone D.;Rinaldi S.;Rossi P.Membro del Collaboration Group
;Palma P.
2019-01-01
Abstract
Assays to estimate human immunodeficiency virus (HIV) reservoir size require large amounts of blood, which represents a drawback especially in pediatric settings. We investigated whether HIV-antibody repertoire could estimate the viral reservoir size. Moreover, we assessed the magnitude of HIV-antibody response as a predictor of time of antiretroviral therapy (ART) initiation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
