Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing. We aimed to assess the effect of a sucrose octasulfate dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ulcers.

Edmonds, M., Lazaro-Martinez, J.l., Alfayate-Garcia, J.m., Martini, J., Petit, J.-., Rayman, G., et al. (2018). Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial. THE LANCET DIABETES & ENDOCRINOLOGY, 6(3), 186-196 [10.1016/S2213-8587(17)30438-2].

Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial

Uccioli L.;
2018-01-01

Abstract

Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing. We aimed to assess the effect of a sucrose octasulfate dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ulcers.
2018
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/13 - ENDOCRINOLOGIA
English
Aged; Anti-Ulcer Agents; Diabetic Foot; Diabetic Neuropathies; Double-Blind Method; Female; Humans; International Agencies; Ischemia; Male; Prognosis; Sucrose; Bandages
Edmonds, M., Lazaro-Martinez, J.l., Alfayate-Garcia, J.m., Martini, J., Petit, J.-., Rayman, G., et al. (2018). Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial. THE LANCET DIABETES & ENDOCRINOLOGY, 6(3), 186-196 [10.1016/S2213-8587(17)30438-2].
Edmonds, M; Lazaro-Martinez, Jl; Alfayate-Garcia, Jm; Martini, J; Petit, J-; Rayman, G; Lobmann, R; Uccioli, L; Sauvadet, A; Bohbot, S; Kerihuel, J-; Piaggesi, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/228228
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