Complement system dysfunction in terms of upregulation, downregulation, or dysregulation can create an imbalance of both host defense and inflammatory response leading to autoimmunity. In this review, we aimed at describing the role of complement system in host defense to inflection and in autoimmunity starting from the evidence from primary and secondary complement system deficiencies.
Conigliaro, P., Triggianese, P., Ballanti, E., Perricone, C., Perricone, R., Chimenti, M.s. (2019). Complement, infection, and autoimmunity. CURRENT OPINION IN RHEUMATOLOGY, 31(5), 532-541 [10.1097/BOR.0000000000000633].
Complement, infection, and autoimmunity
Conigliaro P.;Triggianese P.;Ballanti E.;Perricone R.;Chimenti M. S.
2019-01-01
Abstract
Complement system dysfunction in terms of upregulation, downregulation, or dysregulation can create an imbalance of both host defense and inflammatory response leading to autoimmunity. In this review, we aimed at describing the role of complement system in host defense to inflection and in autoimmunity starting from the evidence from primary and secondary complement system deficiencies.File in questo prodotto:
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