Insulin-resistance is one of the main factors responsible for the onset and progression of Metabolic Syndrome (MetS). Among all polyphenols, the effects of flavonoids and their main food sources on insulin sensitivity have been widely evaluated in molecular and clinical studies. The aim of this review is to analyse the data observed in vitro, in vivo and in clinical trials concerning the effects of flavonoids on insulin resistance and to determine the molecular mechanisms with which flavonoids interact with insulin signaling.

Russo, B., Picconi, F., Malandrucco, I., Frontoni, S. (2019). Flavonoids and insulin-resistance: from molecular evidences to clinical trials. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(9), 2061 [10.3390/ijms20092061].

Flavonoids and insulin-resistance: from molecular evidences to clinical trials

Picconi F.;Frontoni S.
2019-01-01

Abstract

Insulin-resistance is one of the main factors responsible for the onset and progression of Metabolic Syndrome (MetS). Among all polyphenols, the effects of flavonoids and their main food sources on insulin sensitivity have been widely evaluated in molecular and clinical studies. The aim of this review is to analyse the data observed in vitro, in vivo and in clinical trials concerning the effects of flavonoids on insulin resistance and to determine the molecular mechanisms with which flavonoids interact with insulin signaling.
2019
Pubblicato
Rilevanza internazionale
Recensione
Esperti anonimi
Settore MED/13 - ENDOCRINOLOGIA
English
flavonoids; insulin-resistance; metabolic syndrome
Russo, B., Picconi, F., Malandrucco, I., Frontoni, S. (2019). Flavonoids and insulin-resistance: from molecular evidences to clinical trials. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(9), 2061 [10.3390/ijms20092061].
Russo, B; Picconi, F; Malandrucco, I; Frontoni, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/217068
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