Matrix vesicles (MVs) are released from hypertrophic chondrocytes and from mature osteoblasts, the cells responsible for endochondral and membranous ossification. Under pathological conditions, they can also be released from cells of non-skeletal tissues such as vascular smooth muscle cells. MVs are extracellular vesicles of approximately 100-300nm diameter harboring the biochemical machinery needed to induce mineralization.

Bottini, M., Mebarek, S., Anderson, K.l., Strzelecka-Kiliszek, A., Bozycki, L., Simao, A., et al. (2018). Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1862(3), 532-546 [10.1016/j.bbagen.2017.11.005].

Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models

Bottini M.;
2018-01-01

Abstract

Matrix vesicles (MVs) are released from hypertrophic chondrocytes and from mature osteoblasts, the cells responsible for endochondral and membranous ossification. Under pathological conditions, they can also be released from cells of non-skeletal tissues such as vascular smooth muscle cells. MVs are extracellular vesicles of approximately 100-300nm diameter harboring the biochemical machinery needed to induce mineralization.
2018
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/10 - BIOCHIMICA
English
Con Impact Factor ISI
Atomic force microscopy; Electron microscopy; Lipid raft; Matrix vesicles; Mineralization; Proteoliposomes; Animals; Apatites; Biomimetic Materials; Calcification, Physiologic; Calcinosis; Chondrocytes; Collagen; Extracellular Matrix; Humans; Hypertrophy; Membrane Microdomains; Minerals; Models, Biological; Organelle Biogenesis; Osteoblasts; Proteolipids; Specimen Handling; Vascular Calcification; Extracellular Vesicles
https://www.sciencedirect.com/science/article/abs/pii/S0304416517303562?via=ihub
Bottini, M., Mebarek, S., Anderson, K.l., Strzelecka-Kiliszek, A., Bozycki, L., Simao, A., et al. (2018). Matrix vesicles from chondrocytes and osteoblasts: Their biogenesis, properties, functions and biomimetic models. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1862(3), 532-546 [10.1016/j.bbagen.2017.11.005].
Bottini, M; Mebarek, S; Anderson, Kl; Strzelecka-Kiliszek, A; Bozycki, L; Simao, Ams; Bolean, M; Ciancaglini, P; Pikula, Jb; Pikula, S; Magne, D; Volkmann, N; Hanein, D; Millan, Jl; Buchet, R
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/217034
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