The present study was aimed to investigate the relationships between dysfunction of cortical glucose metabolism as detectable by means of 2-deoxy-2-[18F]fluoro -D-glucose ([18F]FDG) positron emission tomography/x-ray computed tomography (PET/CT) and amyloid burden as detectable by means of 4-(E)-2-[4-(2-2-[2-[18F]fluoroethoxy]ethoxyethoxy)phenyl]vinyl-N-methylaniline (florbetaben; [18F]FBB) in a group of patients affected by Alzheimer's disease (AD).
Chiaravalloti, A., Castellano, A.e., Ricci, M., Barbagallo, G., Sannino, P., Ursini, F., et al. (2018). Coupled Imaging with [ 18 F]FBB and [ 18 F]FDG in AD Subjects Show a Selective Association Between Amyloid Burden and Cortical Dysfunction in the Brain. MOLECULAR IMAGING AND BIOLOGY, 20(4), 659-666 [10.1007/s11307-018-1167-1].
Coupled Imaging with [ 18 F]FBB and [ 18 F]FDG in AD Subjects Show a Selective Association Between Amyloid Burden and Cortical Dysfunction in the Brain
Chiaravalloti A.;Schillaci O.
2018-08-01
Abstract
The present study was aimed to investigate the relationships between dysfunction of cortical glucose metabolism as detectable by means of 2-deoxy-2-[18F]fluoro -D-glucose ([18F]FDG) positron emission tomography/x-ray computed tomography (PET/CT) and amyloid burden as detectable by means of 4-(E)-2-[4-(2-2-[2-[18F]fluoroethoxy]ethoxyethoxy)phenyl]vinyl-N-methylaniline (florbetaben; [18F]FBB) in a group of patients affected by Alzheimer's disease (AD).| File | Dimensione | Formato | |
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