BACKGROUND: Breast metastases from extra mammary tumors are extremely rare. CASE REPORT: Here we report the case of a 50-year-old female with histologically-confirmed gastric cancer metastasis to the breast who was adequately treated with loco-regional hyperthermia plus standard second-line chemotherapy (paclitaxel plus ramucirumab). The best response achieved was a relatively long disease stabilization. CONCLUSION: Chemotherapy plus regional hyperthermia has been shown to have a synergistic antitumor effect and possible favorable immunomodulatory effects. Such an approach merits further investigation especially for the treatment of rare superficial metastatic sites.

Lucchetti, J., Formica, V., Giuliano, G., Coletta, D., Gargano, L., Morosetti, D., et al. (2018). Case report of a patient with breast metastasis from gastric cancer treated with paclitaxel and ramucirumab plus regional hyperthermia. ANTICANCER RESEARCH, 38(11), 6561-6564 [10.21873/anticanres.13022].

Case report of a patient with breast metastasis from gastric cancer treated with paclitaxel and ramucirumab plus regional hyperthermia

Formica V.;Morosetti D.;Sileri P.;Palmieri G.;Roselli M.
2018-01-01

Abstract

BACKGROUND: Breast metastases from extra mammary tumors are extremely rare. CASE REPORT: Here we report the case of a 50-year-old female with histologically-confirmed gastric cancer metastasis to the breast who was adequately treated with loco-regional hyperthermia plus standard second-line chemotherapy (paclitaxel plus ramucirumab). The best response achieved was a relatively long disease stabilization. CONCLUSION: Chemotherapy plus regional hyperthermia has been shown to have a synergistic antitumor effect and possible favorable immunomodulatory effects. Such an approach merits further investigation especially for the treatment of rare superficial metastatic sites.
Online ahead of print
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/06 - Oncologia Medica
English
Breast; case report; gastric cancer; metastasis; regional hyperthermia; Antibodies, Monoclonal; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Hyperthermia, Induced; Middle Aged; Paclitaxel; Stomach Neoplasms; Treatment Outcome
Lucchetti, J., Formica, V., Giuliano, G., Coletta, D., Gargano, L., Morosetti, D., et al. (2018). Case report of a patient with breast metastasis from gastric cancer treated with paclitaxel and ramucirumab plus regional hyperthermia. ANTICANCER RESEARCH, 38(11), 6561-6564 [10.21873/anticanres.13022].
Lucchetti, J; Formica, V; Giuliano, G; Coletta, D; Gargano, L; Morosetti, D; Sileri, P; Palmieri, G; Roselli, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/211463
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