Recent studies have shown the increasing relevance of allergic sensitization to Can f 5 (a prostatic kallikrein), which is an androgen-regulated protein expressed in the prostate and detectable only in male dogs. Can f 5 can be a prevalent or exclusive sensitizing agent in a considerable percentage of dog-allergic patients. Its specific allergenic characteristics are able to induce possible negative as well as positive clinical effects in individuals sensitized to dogs. In the present article we pointed out the possible pros or cons of sensitization to this allergen in real life. Further studies should be carried out to correctly assess some peculiar characteristics of Can f 5, in order to support the most of positive aspects and remedy at best the negative effects.

Liccardi, G., Calzetta, L., Salzillo, A., Apicella, G., Piccolo, A., Di Maro, E., et al. (2018). Dog allergy: Can a prevalent or exclusive sensitization to can f 5 be considered a lucky or negative event in “real life”?. EUROPEAN ANNALS OF ALLERGY AND CLINICAL IMMUNOLOGY, 50(6), 283-285 [10.23822/EurAnnACI.1764-1489.41].

Dog allergy: Can a prevalent or exclusive sensitization to can f 5 be considered a lucky or negative event in “real life”?

Calzetta L.;Rogliani P.
2018-01-01

Abstract

Recent studies have shown the increasing relevance of allergic sensitization to Can f 5 (a prostatic kallikrein), which is an androgen-regulated protein expressed in the prostate and detectable only in male dogs. Can f 5 can be a prevalent or exclusive sensitizing agent in a considerable percentage of dog-allergic patients. Its specific allergenic characteristics are able to induce possible negative as well as positive clinical effects in individuals sensitized to dogs. In the present article we pointed out the possible pros or cons of sensitization to this allergen in real life. Further studies should be carried out to correctly assess some peculiar characteristics of Can f 5, in order to support the most of positive aspects and remedy at best the negative effects.
2018
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/10 - MALATTIE DELL'APPARATO RESPIRATORIO
English
Con Impact Factor ISI
Can f 5; allergic rhinitis; allergic sensitization; bronchial asthma; dog; dog allergy; hypersensitivity
Liccardi, G., Calzetta, L., Salzillo, A., Apicella, G., Piccolo, A., Di Maro, E., et al. (2018). Dog allergy: Can a prevalent or exclusive sensitization to can f 5 be considered a lucky or negative event in “real life”?. EUROPEAN ANNALS OF ALLERGY AND CLINICAL IMMUNOLOGY, 50(6), 283-285 [10.23822/EurAnnACI.1764-1489.41].
Liccardi, G; Calzetta, L; Salzillo, A; Apicella, G; Piccolo, A; Di Maro, E; Rogliani, P
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/209560
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