Systemic adjuvant treatment might mitigate the high risk of disease recurrence in patients with resected stage IIC-III melanoma. The BRIM8 study evaluated adjuvant vemurafenib monotherapy in patients with resected, BRAFV600 mutation-positive melanoma.

Maio, M., Lewis, K., Demidov, L., Mandala, M., Bondarenko, I., Ascierto, P.a., et al. (2018). Adjuvant vemurafenib in resected, BRAFV600mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial. THE LANCET ONCOLOGY, 19(4), 510-520 [10.1016/S1470-2045(18)30106-2].

Adjuvant vemurafenib in resected, BRAFV600mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

Herbert C.;Bianchi L.;
2018-01-01

Abstract

Systemic adjuvant treatment might mitigate the high risk of disease recurrence in patients with resected stage IIC-III melanoma. The BRIM8 study evaluated adjuvant vemurafenib monotherapy in patients with resected, BRAFV600 mutation-positive melanoma.
2018
Online ahead of print
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/35 - MALATTIE CUTANEE E VENEREE
English
Maio, M., Lewis, K., Demidov, L., Mandala, M., Bondarenko, I., Ascierto, P.a., et al. (2018). Adjuvant vemurafenib in resected, BRAFV600mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial. THE LANCET ONCOLOGY, 19(4), 510-520 [10.1016/S1470-2045(18)30106-2].
Maio, M; Lewis, K; Demidov, L; Mandala, M; Bondarenko, I; Ascierto, Pa; Herbert, C; Mackiewicz, A; Rutkowski, P; Guminski, A; Goodman, Gr; Simmons, B;...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/201579
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