Microfluidic impedance-based devices with coplanar electrode layout represent an attractive tool for low-cost, label-free, single-cell analysis. However, their usefulness has long been limited by the positional dependence of the measured signals, i.e., identical particles traveling along different paths provide different traces. In this paper we show that it is possible to significantly reduce this unwanted effect via straightforward signal processing, by exploiting the richness of the information contained in the recorded traces.
Errico, V., Ninno, A., Bertani, F., Businaro, L., Bisegna, P., Caselli, F. (2017). Mitigating positional dependence in coplanar electrode coulter-type microfluidic devices. SENSORS AND ACTUATORS. B, CHEMICAL, 247, 580-586 [10.1016/j.snb.2017.03.035].
Mitigating positional dependence in coplanar electrode coulter-type microfluidic devices
Bisegna, P
;Caselli F
2017-01-01
Abstract
Microfluidic impedance-based devices with coplanar electrode layout represent an attractive tool for low-cost, label-free, single-cell analysis. However, their usefulness has long been limited by the positional dependence of the measured signals, i.e., identical particles traveling along different paths provide different traces. In this paper we show that it is possible to significantly reduce this unwanted effect via straightforward signal processing, by exploiting the richness of the information contained in the recorded traces.File | Dimensione | Formato | |
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