Fullerene Black (FB) and Extracted Fullerene Black (EFB) were used in modified screen‐printed electrodes producing electrochemical transducers (FB‐SPEs and EFB‐SPEs). A complete electrochemical study was performed and the best results are obtained working with FB‐SPEs, especially in terms of: 1. improved electron‐transfer kinetic mechanisms and 2. sensitivity and selectivity toward Acetaminophen (Ac) and Guanine (G). These latter represent two important electro‐active targets to quantify in medicine field application, because: Ac is a preferred alternative (as analgesic‐antipyretic agent) to aspirin, particularly for patients who cannot tolerate aspirin; the oxidation signal of G is useful for the fabrication of emerging analytical tools, such as DNA chipsand user‐friendly diagnostic devices. Ac and G are quantify by using FB‐SPEs electrochemical devices, with an extended linearity (1–300 μM for Ac; 0.1–300 μM for G), an excellent sensitivity (2.82 μA μM−1 cm−2 in the case of Ac; and 0.183 μA μM−1 cm−2 in the case of G), a low detection limit (0.01 μM for Ac; 0.005 μM for G), a very good reproducibility (both: intra‐; inter‐electrodes reproducibility RSD % ranging from 0.3–0.5 for Ac; and 0.50–0.85 for G) and a very fast response time (6 s for Ac; 5 s in the case of G). In addition, high selectivity is obtained at FB‐SPEs, meaning that the FB‐SPEs electrochemical transducers are suitable to simultaneously quantify Ac and G in real samples, having several different (highly concentrated) interference.

Valentini, F., Ciambella, E., Cataldo, F., Calcaterra, A., Menegatti, L., & Talamo, M. (2017). Fullerene Black Modified Screen Printed Electrodes for the Quantification of Acetaminophen and Guanine. ELECTROANALYSIS, 29(12), 2863-2872 [10.1002/elan.201700426].

Fullerene Black Modified Screen Printed Electrodes for the Quantification of Acetaminophen and Guanine

Valentini F.
Writing – Original Draft Preparation
;
Talamo M.
Funding Acquisition
2017-12

Abstract

Fullerene Black (FB) and Extracted Fullerene Black (EFB) were used in modified screen‐printed electrodes producing electrochemical transducers (FB‐SPEs and EFB‐SPEs). A complete electrochemical study was performed and the best results are obtained working with FB‐SPEs, especially in terms of: 1. improved electron‐transfer kinetic mechanisms and 2. sensitivity and selectivity toward Acetaminophen (Ac) and Guanine (G). These latter represent two important electro‐active targets to quantify in medicine field application, because: Ac is a preferred alternative (as analgesic‐antipyretic agent) to aspirin, particularly for patients who cannot tolerate aspirin; the oxidation signal of G is useful for the fabrication of emerging analytical tools, such as DNA chipsand user‐friendly diagnostic devices. Ac and G are quantify by using FB‐SPEs electrochemical devices, with an extended linearity (1–300 μM for Ac; 0.1–300 μM for G), an excellent sensitivity (2.82 μA μM−1 cm−2 in the case of Ac; and 0.183 μA μM−1 cm−2 in the case of G), a low detection limit (0.01 μM for Ac; 0.005 μM for G), a very good reproducibility (both: intra‐; inter‐electrodes reproducibility RSD % ranging from 0.3–0.5 for Ac; and 0.50–0.85 for G) and a very fast response time (6 s for Ac; 5 s in the case of G). In addition, high selectivity is obtained at FB‐SPEs, meaning that the FB‐SPEs electrochemical transducers are suitable to simultaneously quantify Ac and G in real samples, having several different (highly concentrated) interference.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore CHIM/01 - Chimica Analitica
English
Con Impact Factor ISI
Valentini, F., Ciambella, E., Cataldo, F., Calcaterra, A., Menegatti, L., & Talamo, M. (2017). Fullerene Black Modified Screen Printed Electrodes for the Quantification of Acetaminophen and Guanine. ELECTROANALYSIS, 29(12), 2863-2872 [10.1002/elan.201700426].
Valentini, F; Ciambella, E; Cataldo, F; Calcaterra, A; Menegatti, L; Talamo, M
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Fullerene Black Modified Screen Printed Electrodes for the.pdf

accesso solo dalla rete interna

Licenza: Non specificato
Dimensione 921.33 kB
Formato Adobe PDF
921.33 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/198686
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 10
  • ???jsp.display-item.citation.isi??? 8
social impact