Chemotherapy and hematopoietic stem cell transplantation (HSCT) are the current treatments for patients with hematological diseases; they result in myelosuppression, and increase the susceptibility of patients to severe infections. The oral cavity is a potential site of complications in HSCT patients, because it is the entrance for agents that can cause systemic infections; it is one of the most frequent locations for side effects deriving from conditioning therapy. The importance of dental pre-chemotherapy and transplant prescription is often stressed, since both therapies depress the immune system and platelets, making each intervention at this stage a high risk. The aim of this article is to review the potential complications of HSCT, and to extrapolate from the scientific literature the treatments and timeframes in which dental therapies can be performed, avoiding important risks for patients.

Bollero, P., Passarelli Pier, C., D'Addona, A., Pasquantonio, G., Mancini, M., Condò, R., et al. (2018). Oral management of adult patients undergoing hematopoietic stem cell transplantation. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 22(4), 876-887 [10.26355/eurrev_201802_14365].

Oral management of adult patients undergoing hematopoietic stem cell transplantation.

Bollero Patrizio;D'Addona Antonio;Pasquantonio Guido;Mancini Manuele;Condò Roberta;Cerroni Loredana
2018-02

Abstract

Chemotherapy and hematopoietic stem cell transplantation (HSCT) are the current treatments for patients with hematological diseases; they result in myelosuppression, and increase the susceptibility of patients to severe infections. The oral cavity is a potential site of complications in HSCT patients, because it is the entrance for agents that can cause systemic infections; it is one of the most frequent locations for side effects deriving from conditioning therapy. The importance of dental pre-chemotherapy and transplant prescription is often stressed, since both therapies depress the immune system and platelets, making each intervention at this stage a high risk. The aim of this article is to review the potential complications of HSCT, and to extrapolate from the scientific literature the treatments and timeframes in which dental therapies can be performed, avoiding important risks for patients.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/28 - Malattie Odontostomatologiche
English
Con Impact Factor ISI
Stem cell, Transplantation, Oral management, Complications of HSCT, Chemotherapy, Hematopoietic
Bollero, P., Passarelli Pier, C., D'Addona, A., Pasquantonio, G., Mancini, M., Condò, R., et al. (2018). Oral management of adult patients undergoing hematopoietic stem cell transplantation. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 22(4), 876-887 [10.26355/eurrev_201802_14365].
Bollero, P; Passarelli Pier, C; D'Addona, A; Pasquantonio, G; Mancini, M; Condò, R; Cerroni, L
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/198575
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