We have previously shown that antagonism of the mineralocorticoid receptor (MR) results in a potent antiadipogenic activity, in vitro and in vivo. Excessive glucocorticoid exposure is associated with obesity and related disorders in humans and mice.

Mammi, C., Marzolla, V., Armani, A., Feraco, A., Antelmi, A., Maslak, E., et al. (2016). A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet. INTERNATIONAL JOURNAL OF OBESITY, 40(6), 964-972 [10.1038/ijo.2016.13].

A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet

FERACO, ALESSANDRA;FABBRI, ANDREA;CAPRIO, MASSIMILIANO
2016-01-01

Abstract

We have previously shown that antagonism of the mineralocorticoid receptor (MR) results in a potent antiadipogenic activity, in vitro and in vivo. Excessive glucocorticoid exposure is associated with obesity and related disorders in humans and mice.
2016
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/13 - ENDOCRINOLOGIA
English
Con Impact Factor ISI
Mammi, C., Marzolla, V., Armani, A., Feraco, A., Antelmi, A., Maslak, E., et al. (2016). A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet. INTERNATIONAL JOURNAL OF OBESITY, 40(6), 964-972 [10.1038/ijo.2016.13].
Mammi, C; Marzolla, V; Armani, A; Feraco, A; Antelmi, A; Maslak, E; Chlopicki, S; Cinti, F; Hunt, H; Fabbri, A; Caprio, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/198184
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