We evaluated growth indices in two cohorts of Malawian infants exposed to tenofovir, lamivudine and efavirenz in utero and during 12 months of breastfeeding, and to stavudine/zidovudine, lamivudine and nevirapine in utero and during 6 months of breastfeeding. Growth indices were similar in the two cohorts at one and 6 months but were significantly better in the first group at 12 months, suggesting no negative effect of tenofovir and a significant benefit of extended breastfeeding.
Liotta, G., Floridia, M., Andreotti, M., Jere, H., Sagno, J., Marazzi, M., et al. (2016). Growth indices in breastfed infants pre and postnatally exposed to tenofovir compared with tenofovir-unexposed infants. AIDS, 30(3), 525-527 [10.1097/QAD.0000000000000944].
Growth indices in breastfed infants pre and postnatally exposed to tenofovir compared with tenofovir-unexposed infants
LIOTTA, GIUSEPPE;BUONOMO, ERSILIA;SCARCELLA, PAOLA;MANCINELLI, SANDRO;PALOMBI, LEONARDO
2016-01-01
Abstract
We evaluated growth indices in two cohorts of Malawian infants exposed to tenofovir, lamivudine and efavirenz in utero and during 12 months of breastfeeding, and to stavudine/zidovudine, lamivudine and nevirapine in utero and during 6 months of breastfeeding. Growth indices were similar in the two cohorts at one and 6 months but were significantly better in the first group at 12 months, suggesting no negative effect of tenofovir and a significant benefit of extended breastfeeding.| File | Dimensione | Formato | |
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