The cortical input of 117 dentate nucleus neurons projecting either to the red nucleus (73 cells) or to the inferior olive (44 units) was studied electrophysiologically in rats. The majority of cells in both groups responded to electrical stimulation of discrete sites of the contralateral motor cortex. However, activation latencies from the same cortical focus were shorter for neurons projecting to the red nucleus than for olivary-projecting neurons. Principal components analysis pointed out significant differences between the two neuronal subgroups also in the temporal pattern of activity. These results suggest that a motor command might be transmitted through parallel independent channels to cerebellar neurons projecting to different regions of the brainstem.

Giaquinta, G., Casabona, A., Smecca, G., Bosco, G., Perciavalle, V. (1999). Cortical control of cerebellar dentato-rubral and dentato-olivary neurons. NEUROREPORT, 10(14), 3009-3013.

Cortical control of cerebellar dentato-rubral and dentato-olivary neurons

BOSCO, GIANFRANCO;
1999-09-29

Abstract

The cortical input of 117 dentate nucleus neurons projecting either to the red nucleus (73 cells) or to the inferior olive (44 units) was studied electrophysiologically in rats. The majority of cells in both groups responded to electrical stimulation of discrete sites of the contralateral motor cortex. However, activation latencies from the same cortical focus were shorter for neurons projecting to the red nucleus than for olivary-projecting neurons. Principal components analysis pointed out significant differences between the two neuronal subgroups also in the temporal pattern of activity. These results suggest that a motor command might be transmitted through parallel independent channels to cerebellar neurons projecting to different regions of the brainstem.
29-set-1999
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/09 - FISIOLOGIA
English
Electrophysiology; male; extracellular space; nerve net; red nucleus; rats; animals; rats, sprague-dawley; cerebral cortex; electric stimulation; cerebellum; olivary nucleus; motor cortex; neurons; neural pathways; dentate gyrus
Giaquinta, G., Casabona, A., Smecca, G., Bosco, G., Perciavalle, V. (1999). Cortical control of cerebellar dentato-rubral and dentato-olivary neurons. NEUROREPORT, 10(14), 3009-3013.
Giaquinta, G; Casabona, A; Smecca, G; Bosco, G; Perciavalle, V
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/19417
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