The development of bone metastasis from breast cancer results from a functional interaction between tumor cells and osteoclasts or osteoblasts. The main aim of this study was therefore to test the hypothesis that the appearance of breast osteoblast-like cells (BOLCs) in primary mammary lesions is a precursor (and hence an early predictor) of the formation of breast cancer metastases to bone.

Scimeca, M., Antonacci, C., Toschi, N., Giannini, E., Bonfiglio, R., Buonomo, C.o., et al. (2018). Breast Osteoblast-like Cells: A Reliable Early Marker for Bone Metastases From Breast Cancer. CLINICAL BREAST CANCER, 18(4), e659-e669 [10.1016/j.clbc.2017.11.020].

Breast Osteoblast-like Cells: A Reliable Early Marker for Bone Metastases From Breast Cancer

Scimeca M.
Writing – Original Draft Preparation
;
Toschi N.
Membro del Collaboration Group
;
Bonfiglio R.
Membro del Collaboration Group
;
Pistolese C. A.
Membro del Collaboration Group
;
Tarantino U.
Funding Acquisition
;
Bonanno E.
Project Administration
;
BUONOMO, ORESTE CLAUDIO
2018-01-01

Abstract

The development of bone metastasis from breast cancer results from a functional interaction between tumor cells and osteoclasts or osteoblasts. The main aim of this study was therefore to test the hypothesis that the appearance of breast osteoblast-like cells (BOLCs) in primary mammary lesions is a precursor (and hence an early predictor) of the formation of breast cancer metastases to bone.
2018
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/08 - ANATOMIA PATOLOGICA
English
Bone metastasis; Bone morphogenetic proteins (BMPs); Epithelial to mesenchymal transition (EMT); PTX3; RANKL
Scimeca, M., Antonacci, C., Toschi, N., Giannini, E., Bonfiglio, R., Buonomo, C.o., et al. (2018). Breast Osteoblast-like Cells: A Reliable Early Marker for Bone Metastases From Breast Cancer. CLINICAL BREAST CANCER, 18(4), e659-e669 [10.1016/j.clbc.2017.11.020].
Scimeca, M; Antonacci, C; Toschi, N; Giannini, E; Bonfiglio, R; Buonomo, Co; Pistolese, Ca; Tarantino, U; Bonanno, E; Buonomo, Oc
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/194136
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