We report on a male child born in Rumania, adopted by an Italian family, and who at 10 years of age was submitted to interferon-alpha 2a therapy for chronic hepatitis B. About 30 days after the beginning of the treatment he developed hypomanic mood and psychogenic seizures. Psychological evaluation showed hyperactivity, distractibility, excessive talkativeness, grandiosity and racing thoughts. Temperamental traits were characterized by an elevated emotionality. The patient was successfully administered risperidone and cognitive-behavioral therapy; six months of treatment with interferon led to positive outcome of hepatitis B. Since affective symptoms may occur in children treated with IFN, a careful evaluation of psychiatric disturbances and adequate intervention are needed.

Mazzone, L., & Mugno, D. (2007). Hypomanic mood in a child patient treated with interferon-α 2a: Case report. BRAIN & DEVELOPMENT, 29(10), 666-669 [10.1016/j.braindev.2007.03.010].

Hypomanic mood in a child patient treated with interferon-α 2a: Case report

Mazzone L.
;
2007

Abstract

We report on a male child born in Rumania, adopted by an Italian family, and who at 10 years of age was submitted to interferon-alpha 2a therapy for chronic hepatitis B. About 30 days after the beginning of the treatment he developed hypomanic mood and psychogenic seizures. Psychological evaluation showed hyperactivity, distractibility, excessive talkativeness, grandiosity and racing thoughts. Temperamental traits were characterized by an elevated emotionality. The patient was successfully administered risperidone and cognitive-behavioral therapy; six months of treatment with interferon led to positive outcome of hepatitis B. Since affective symptoms may occur in children treated with IFN, a careful evaluation of psychiatric disturbances and adequate intervention are needed.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/39 - Neuropsichiatria Infantile
English
Con Impact Factor ISI
Bipolar Disorder; Child; Humans; Immunologic Factors; Interferon-alpha; Male
Mazzone, L., & Mugno, D. (2007). Hypomanic mood in a child patient treated with interferon-α 2a: Case report. BRAIN & DEVELOPMENT, 29(10), 666-669 [10.1016/j.braindev.2007.03.010].
Mazzone, L; Mugno, D
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/194075
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