There is limited research on clinical features related to age of presentation of the Attenuated Psychosis Syndrome in children and adolescents (CAD). Based on findings in CAD with psychosis, we hypothesized that an older age at presentation of Attenuated Psychosis Syndrome would be associated with less severe symptoms and better psychosocial functioning than presentation in childhood or younger adolescence. Ninety-four CAD (age 9-18) meeting Attenuated Psychosis Syndrome criteria participated in the study. The sample was divided and compared according to the age of presentation of Attenuated Psychosis Syndrome (9-14 vs 15-18 years). The predictive value of age of Attenuated Psychosis Syndrome presentation was investigated using receiver operating characteristic (ROC)-curve calculations. The two Attenuated Psychosis Syndrome groups were homogeneous in terms of gender distribution, IQ scores and comorbid diagnoses. Older Attenuated Psychosis Syndrome patients showed better functioning and lower depressive scores. ROC curves revealed that severity of functional impairment was best predicted using an age of presentation cut-off of 14.9 years for social functioning and 15.9 years for role functioning. This study partially confirmed our hypothesis; older age at presentation of Attenuated Psychosis Syndrome was associated with less functional impairment, but age was not associated with psychotic symptoms.

Ribolsi, M., Lin, A., Wardenaar, K.j., Pontillo, M., Mazzone, L., Vicari, S., et al. (2017). Clinical presentation of Attenuated Psychosis Syndrome in children and adolescents: Is there an age effect?. PSYCHIATRY RESEARCH, 252, 169-174 [10.1016/j.psychres.2017.02.050].

Clinical presentation of Attenuated Psychosis Syndrome in children and adolescents: Is there an age effect?

Ribolsi M.;Mazzone L.
;
2017-06

Abstract

There is limited research on clinical features related to age of presentation of the Attenuated Psychosis Syndrome in children and adolescents (CAD). Based on findings in CAD with psychosis, we hypothesized that an older age at presentation of Attenuated Psychosis Syndrome would be associated with less severe symptoms and better psychosocial functioning than presentation in childhood or younger adolescence. Ninety-four CAD (age 9-18) meeting Attenuated Psychosis Syndrome criteria participated in the study. The sample was divided and compared according to the age of presentation of Attenuated Psychosis Syndrome (9-14 vs 15-18 years). The predictive value of age of Attenuated Psychosis Syndrome presentation was investigated using receiver operating characteristic (ROC)-curve calculations. The two Attenuated Psychosis Syndrome groups were homogeneous in terms of gender distribution, IQ scores and comorbid diagnoses. Older Attenuated Psychosis Syndrome patients showed better functioning and lower depressive scores. ROC curves revealed that severity of functional impairment was best predicted using an age of presentation cut-off of 14.9 years for social functioning and 15.9 years for role functioning. This study partially confirmed our hypothesis; older age at presentation of Attenuated Psychosis Syndrome was associated with less functional impairment, but age was not associated with psychotic symptoms.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/39 - Neuropsichiatria Infantile
English
Adolescents; Attenuated psychosis syndrome; Children; Functioning; Psychosocial; Psychotic symptoms; Ultra high risk; Adolescent; Child; Comorbidity; Depression; Female; Humans; Male; Predictive Value of Tests; Psychotic Disorders; ROC Curve; Social Behavior; Syndrome; Age Factors; Disability Evaluation
Ribolsi, M., Lin, A., Wardenaar, K.j., Pontillo, M., Mazzone, L., Vicari, S., et al. (2017). Clinical presentation of Attenuated Psychosis Syndrome in children and adolescents: Is there an age effect?. PSYCHIATRY RESEARCH, 252, 169-174 [10.1016/j.psychres.2017.02.050].
Ribolsi, M; Lin, A; Wardenaar, Kj; Pontillo, M; Mazzone, L; Vicari, S; Armando, M
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/194031
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