Recent studies have reported a relationship between the abundance of epicardial adipose tissue (EAT) and the risk of cardiovascular diseases including atrial fibrillation (AF). However, the underlying mechanisms are unknown. The aim of this study was to examine the effects of the secretome of human EAT on the histological properties of the myocardium.

Venteclef, N., Guglielmi, V., Balse, E., Gaborit, B., Cotillard, A., Atassi, F., et al. (2015). Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines. EUROPEAN HEART JOURNAL, 36(13), 795-805 [10.1093/eurheartj/eht099].

Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines

Guglielmi V.;
2015

Abstract

Recent studies have reported a relationship between the abundance of epicardial adipose tissue (EAT) and the risk of cardiovascular diseases including atrial fibrillation (AF). However, the underlying mechanisms are unknown. The aim of this study was to examine the effects of the secretome of human EAT on the histological properties of the myocardium.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/09 - Medicina Interna
English
Con Impact Factor ISI
Activin A; Atrial fibrillation; Atrial fibrosis; Epicardial adipose tissue; Myocardial fibrosis; Activins; Adipokines; Adipose Tissue; Animals; Atrial Fibrillation; Atrial Remodeling; Cells, Cultured; Female; Fibrosis; Heart Atria; Humans; Male; Matrix Metalloproteinase 8; Middle Aged; Myocardium; Rats; Subcutaneous Fat
Venteclef, N., Guglielmi, V., Balse, E., Gaborit, B., Cotillard, A., Atassi, F., et al. (2015). Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines. EUROPEAN HEART JOURNAL, 36(13), 795-805 [10.1093/eurheartj/eht099].
Venteclef, N; Guglielmi, V; Balse, E; Gaborit, B; Cotillard, A; Atassi, F; Amour, J; Leprince, P; Dutour, A; Clement, K; Hatem, Sn
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/192133
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