Herpes labialis (HL) is the most common manifestation of recurrent oral herpes simplex virus type-1 (HSV-1) infection. Between 20% and 40% of the population is affected by recurrent HL. The biological basis for the difference between HSV-1-infected individuals who do and who do not suffer recurrences, has long been investigated. Interferon (IFN)-alpha and IFN-lambda are essential for antiviral immunity, but the precise role of IFN-lambda in vivo is not yet well understood.
Pica, F., Volpi, A., Gaziano, R., Garaci, E. (2010). Interferon-lambda in immunocompetent individuals with a history of recurrent herpes labialis. ANTIVIRAL THERAPY, 15(5), 737-743 [10.3851/IMP1610].
Interferon-lambda in immunocompetent individuals with a history of recurrent herpes labialis
PICA, FRANCESCA;VOLPI, ANTONIO;GAZIANO, ROBERTA;GARACI, ENRICO
2010-01-01
Abstract
Herpes labialis (HL) is the most common manifestation of recurrent oral herpes simplex virus type-1 (HSV-1) infection. Between 20% and 40% of the population is affected by recurrent HL. The biological basis for the difference between HSV-1-infected individuals who do and who do not suffer recurrences, has long been investigated. Interferon (IFN)-alpha and IFN-lambda are essential for antiviral immunity, but the precise role of IFN-lambda in vivo is not yet well understood.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
