Long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) are burdened by the potential risk of inducing cardiovascular serious adverse events (SAEs) in COPD patients. Since the risk of combining a LABA with a LAMA could be greater, we have carried out a quantitative synthesis to investigate the cardiovascular safety profile of LABA/LAMA fixed-dose combinations (FDCs).

Rogliani, P., Matera, M.g., Ora, J., Cazzola, M., & Calzetta, L. (2017). The impact of dual bronchodilation on cardiovascular serious adverse events and mortality in COPD: A quantitative synthesis. INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 12, 3469-3485 [10.2147/COPD.S146338].

The impact of dual bronchodilation on cardiovascular serious adverse events and mortality in COPD: A quantitative synthesis

Rogliani P.
;
Cazzola M.;Calzetta L.
2017

Abstract

Long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) are burdened by the potential risk of inducing cardiovascular serious adverse events (SAEs) in COPD patients. Since the risk of combining a LABA with a LAMA could be greater, we have carried out a quantitative synthesis to investigate the cardiovascular safety profile of LABA/LAMA fixed-dose combinations (FDCs).
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/10 - Malattie dell'Apparato Respiratorio
English
Con Impact Factor ISI
COPD; LABA/LAMA FDC; cardiovascular safety; meta-analysis; mortality
Rogliani, P., Matera, M.g., Ora, J., Cazzola, M., & Calzetta, L. (2017). The impact of dual bronchodilation on cardiovascular serious adverse events and mortality in COPD: A quantitative synthesis. INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 12, 3469-3485 [10.2147/COPD.S146338].
Rogliani, P; Matera, Mg; Ora, J; Cazzola, M; Calzetta, L
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/191998
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