L’utilizzo della Nadroparina Calcica in donne affette da abortività idiopatica ricorrente

Inherited and acquired thrombophilias are associated with recurrent pregnancy loss(RPL) and venous thromboembolism(VTE). RPL is a major health problem affecting 1-2% of women at the reproductive age. While chromosomal aberration, endocrinologic dysfunctions and uterine abnormalities are etioloogic factors, a cause of RPL could not be identified. Inherited and acquired thrombophilias can be found in 50-65% of women with RPL of unknown cause, as well as in women with other vascular pathologies such peeclampsia, intrauterine restriction and placental abruption. Gestational outcame in woman with inherited thrombphilias who present with RPL is poor with less than 25% of prengnacies resulting in live birth. The purpose of this study is to verify the safe and efficacy of Nadroparin in RPL.