Increasing line of evidence indicates that the NKG2D-activating receptor plays a relevant role in the effector functions of cytotoxic lymphocytes. In this study, we investigated the expression and function of NKG2D in CD8⁺ T cells from chronically HIV-1-infected patients with or without antiretroviral therapy (ART).

Giuliani, E., Vassena, L., Desimio, M., Buonomini, A., Malagnino, V., Andreoni, M., et al. (2015). Expression and Function of NKG2D Is Impaired in CD8+ T Cells of Chronically HIV-1-Infected Patients Without ART. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 70(4), 347-356 [10.1097/QAI.0000000000000792].

Expression and Function of NKG2D Is Impaired in CD8+ T Cells of Chronically HIV-1-Infected Patients Without ART

Malagnino, V;ANDREONI, MASSIMO;
2015-12-01

Abstract

Increasing line of evidence indicates that the NKG2D-activating receptor plays a relevant role in the effector functions of cytotoxic lymphocytes. In this study, we investigated the expression and function of NKG2D in CD8⁺ T cells from chronically HIV-1-infected patients with or without antiretroviral therapy (ART).
1-dic-2015
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/17 - MALATTIE INFETTIVE
English
Con Impact Factor ISI
Adult; Antigens, CD14; Antigens, CD38; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cell Degranulation; Female; Flow Cytometry; HIV Infections; HIV-1; Humans; Male; Membrane Glycoproteins; Middle Aged; NK Cell Lectin-Like Receptor Subfamily K; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; Viral Load; Gene Expression Profiling
Giuliani, E., Vassena, L., Desimio, M., Buonomini, A., Malagnino, V., Andreoni, M., et al. (2015). Expression and Function of NKG2D Is Impaired in CD8+ T Cells of Chronically HIV-1-Infected Patients Without ART. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 70(4), 347-356 [10.1097/QAI.0000000000000792].
Giuliani, E; Vassena, L; Desimio, M; Buonomini, A; Malagnino, V; Andreoni, M; Doria, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/186801
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