Dopamine (DA) is a neurotransmitter belonging to the catecholamine family that plays essential functions in the central nervous system. The main source of DA in the brain derives from dopaminergic neurons in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNpc) that project to different brain regions and exert distinct functions. The VTA targets the hippocampus, nucleus accumbens and cerebral cortex and mediates the control of motivation and reward. In contrast, the SNpc projects mainly to the caudate and putamen nuclei of the striatum and is involved primarily in the control of voluntary movement.

D'Amelio, M., & NISTICO', R.G. (2018). Unlocking the secrets of dopamine in Alzheimer's Disease. PHARMACOLOGICAL RESEARCH, 128, 399-399 [10.1016/j.phrs.2017.06.018].

Unlocking the secrets of dopamine in Alzheimer's Disease

NISTICO', ROBERT GIOVANNI
2018

Abstract

Dopamine (DA) is a neurotransmitter belonging to the catecholamine family that plays essential functions in the central nervous system. The main source of DA in the brain derives from dopaminergic neurons in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNpc) that project to different brain regions and exert distinct functions. The VTA targets the hippocampus, nucleus accumbens and cerebral cortex and mediates the control of motivation and reward. In contrast, the SNpc projects mainly to the caudate and putamen nuclei of the striatum and is involved primarily in the control of voluntary movement.
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English
D'Amelio, M., & NISTICO', R.G. (2018). Unlocking the secrets of dopamine in Alzheimer's Disease. PHARMACOLOGICAL RESEARCH, 128, 399-399 [10.1016/j.phrs.2017.06.018].
D'Amelio, M; Nistico', Rg
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/186246
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