Inflammatory bowel diseases (IBD) evoke a damage-repair process accompanied by the activation of apoptotic genes. Data on transglutaminase (TG) expression in apoptotic cells in inflamed colonic epithelium has not been reported, although TG cross-links proteins within typical apoptotic bodies in various cell lines. In an experimental model of colitis we investigated the expression of different markers of apoptosis related to the degree and development of colonic inflammation.

D'Argenio, G., Farrace, M.g., Cosenza, V., De Ritis, F., Della Valle, N., Manguso, F., et al. (2004). Expression of apoptosis-related proteins in rat with induced colitis. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 19(5), 451-60-460 [10.1007/s00384-004-0585-5].

Expression of apoptosis-related proteins in rat with induced colitis

FARRACE, MARIA GRAZIA;PIACENTINI, MAURO
2004-09-01

Abstract

Inflammatory bowel diseases (IBD) evoke a damage-repair process accompanied by the activation of apoptotic genes. Data on transglutaminase (TG) expression in apoptotic cells in inflamed colonic epithelium has not been reported, although TG cross-links proteins within typical apoptotic bodies in various cell lines. In an experimental model of colitis we investigated the expression of different markers of apoptosis related to the degree and development of colonic inflammation.
set-2004
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/06 - ANATOMIA COMPARATA E CITOLOGIA
English
Animals; Antigens, CD95; Antigens, Surface; Biomarkers; Biopsy; Colitis; Disease Models, Animal; Fas Ligand Protein; In Situ Nick-End Labeling; Ligands; Male; Membrane Glycoproteins; Rats; Rats, Wistar; Transglutaminases; Trinitrobenzenesulfonic Acid; Tumor Suppressor Protein p53; Apoptosis
D'Argenio, G., Farrace, M.g., Cosenza, V., De Ritis, F., Della Valle, N., Manguso, F., et al. (2004). Expression of apoptosis-related proteins in rat with induced colitis. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 19(5), 451-60-460 [10.1007/s00384-004-0585-5].
D'Argenio, G; Farrace, Mg; Cosenza, V; De Ritis, F; Della Valle, N; Manguso, F; Piacentini, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/181458
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