Serum uric acid (UA) has been associated with increased risk of cardiovascular and metabolic diseases. However, the causal mechanisms linking elevated UA levels to cardio-metabolic diseases are still unsettled. One potential explanation for how UA might contribute to cardio-metabolic disease might be its ability to induce systemic inflammation.

Spiga, R., Marini, M.a., Mancuso, E., Di Fatta, C., Fuoco, A., Perticone, F., et al. (2017). Uric Acid Is Associated With Inflammatory Biomarkers and Induces Inflammation Via Activating the NF-κB Signaling Pathway in HepG2 Cells. ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY, ATVBAHA.117.309128 [10.1161/ATVBAHA.117.309128].

Uric Acid Is Associated With Inflammatory Biomarkers and Induces Inflammation Via Activating the NF-κB Signaling Pathway in HepG2 Cells

MARINI, MARIA ADELAIDE;
2017

Abstract

Serum uric acid (UA) has been associated with increased risk of cardiovascular and metabolic diseases. However, the causal mechanisms linking elevated UA levels to cardio-metabolic diseases are still unsettled. One potential explanation for how UA might contribute to cardio-metabolic disease might be its ability to induce systemic inflammation.
Online ahead of print
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/09 - Medicina Interna
English
Con Impact Factor ISI
NF-κB; inflammation; oxidative stress; risk factors; uric acid
Spiga, R., Marini, M.a., Mancuso, E., Di Fatta, C., Fuoco, A., Perticone, F., et al. (2017). Uric Acid Is Associated With Inflammatory Biomarkers and Induces Inflammation Via Activating the NF-κB Signaling Pathway in HepG2 Cells. ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY, ATVBAHA.117.309128 [10.1161/ATVBAHA.117.309128].
Spiga, R; Marini, Ma; Mancuso, E; Di Fatta, C; Fuoco, A; Perticone, F; Andreozzi, F; Mannino, G; Sesti, G
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/180290
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