Fucosyltransferase locus 2 (FUT2) controls the presence or absence of blood group substances (A, B, H) in the saliva and other body secretions. Secretor/non-secretor phenotypes are associated with some metabolic and infectious diseases. ABO and FUT2 contribute to build up oligosaccharide structures of the cell surface that are important for blastocyst adhesion and resistance to microbial invasion. We investigated a possible selection on ABH secretor phenotypes during intrauterine life.
Gloria, F., Magrini, A., Cozzoli, E., Neri, A., Pietroiusti, A., Amante, A., et al. (2011). ABH secretor genetic polymorphism: evidence of intrauterine selection. EUROPEAN JOURNAL OF OBSTETRICS, GYNECOLOGY, AND REPRODUCTIVE BIOLOGY, 154(1), 20-23 [10.1016/j.ejogrb.2010.08.001].
ABH secretor genetic polymorphism: evidence of intrauterine selection
GLORIA, FULVIA;MAGRINI, ANDREA;COZZOLI, ELIANA;NERI, ANNA;PIETROIUSTI, ANTONIO;AMANTE, ADA;BOTTINI, EGIDIO
2011-01-01
Abstract
Fucosyltransferase locus 2 (FUT2) controls the presence or absence of blood group substances (A, B, H) in the saliva and other body secretions. Secretor/non-secretor phenotypes are associated with some metabolic and infectious diseases. ABO and FUT2 contribute to build up oligosaccharide structures of the cell surface that are important for blastocyst adhesion and resistance to microbial invasion. We investigated a possible selection on ABH secretor phenotypes during intrauterine life.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
