V gamma 9V delta 2 T lymphocytes strongly respond to phosphoantigens from Plasmodium parasites. Thus, we analyzed the changes in V gamma 9V delta 2 T-cell function and repertoire during the paroxysm phase of nonendemic malaria infection. During malaria paroxysm, V gamma 9V delta 2 T cells were early activated but rapidly became anergic and finally loose J gamma 1.2 V gamma 9 complementarity-determining region 3 transcripts.

Martini, F., Paglia, M., Montesano, C., Enders, P., Gentile, M., Pauza, C., et al. (2003). V gamma 9V delta 2 T-cell anergy and complementarity-determining region 3-specific depletion during paroxysm of nonendemic malaria infection. INFECTION AND IMMUNITY, 71(5), 2945-2949 [10.1128/IAI.71.5.2945-2949.2003].

V gamma 9V delta 2 T-cell anergy and complementarity-determining region 3-specific depletion during paroxysm of nonendemic malaria infection

MONTESANO, CARLA;COLIZZI, VITTORIO;
2003-05-01

Abstract

V gamma 9V delta 2 T lymphocytes strongly respond to phosphoantigens from Plasmodium parasites. Thus, we analyzed the changes in V gamma 9V delta 2 T-cell function and repertoire during the paroxysm phase of nonendemic malaria infection. During malaria paroxysm, V gamma 9V delta 2 T cells were early activated but rapidly became anergic and finally loose J gamma 1.2 V gamma 9 complementarity-determining region 3 transcripts.
mag-2003
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/04 - PATOLOGIA GENERALE
English
Con Impact Factor ISI
T-Lymphocyte Subsets; HLA-DR Antigens; Complementarity Determining Regions; Receptors, Antigen, T-Cell, gamma-delta; Male; Malaria, Falciparum; Middle Aged; Female; Immune Tolerance; Adult; Humans
Martini, F., Paglia, M., Montesano, C., Enders, P., Gentile, M., Pauza, C., et al. (2003). V gamma 9V delta 2 T-cell anergy and complementarity-determining region 3-specific depletion during paroxysm of nonendemic malaria infection. INFECTION AND IMMUNITY, 71(5), 2945-2949 [10.1128/IAI.71.5.2945-2949.2003].
Martini, F; Paglia, M; Montesano, C; Enders, P; Gentile, M; Pauza, C; Gioia, C; Colizzi, V; Narciso, P; Pucillo, L; Poccia, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/17563
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