Platelet derived growth factor (PDGF) is involved in the development of leiomyomas. The low-molecular-weight phosphoprotein-tyrosine-phosphatase (LMWPTP), controlled by the highly polymorphic acid phosphatase locus 1 (ACP1), is able to dephosphorylate the PDGF receptor. Therefore, we searched for a possible association between ACP1 and leiomyomas.

Ammendola, M., Pietropolli, A., Lista, F., Saccucci, P., Piccione, E., Bottini, E., et al. (2009). Is there an association between uterine leiomyomas and acid phosphatase locus 1 polymorphism?. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 200(1), 110.e1-5 [10.1016/j.ajog.2008.07.033].

Is there an association between uterine leiomyomas and acid phosphatase locus 1 polymorphism?

PIETROPOLLI, ADALGISA;SACCUCCI, PATRIZIA;PICCIONE, EMILIO;BOTTINI, EGIDIO;GLORIA, FULVIA
2009-01-01

Abstract

Platelet derived growth factor (PDGF) is involved in the development of leiomyomas. The low-molecular-weight phosphoprotein-tyrosine-phosphatase (LMWPTP), controlled by the highly polymorphic acid phosphatase locus 1 (ACP1), is able to dephosphorylate the PDGF receptor. Therefore, we searched for a possible association between ACP1 and leiomyomas.
gen-2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/01 - STATISTICA MEDICA
English
Con Impact Factor ISI
Protein Tyrosine Phosphatases; DNA; Female; Polymorphism, Single Nucleotide; Uterine Neoplasms; Genotype; Humans; Statistics, Nonparametric; Protein Isoforms; Leiomyoma; Polymerase Chain Reaction; Proto-Oncogene Proteins; Adult
Ammendola, M., Pietropolli, A., Lista, F., Saccucci, P., Piccione, E., Bottini, E., et al. (2009). Is there an association between uterine leiomyomas and acid phosphatase locus 1 polymorphism?. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 200(1), 110.e1-5 [10.1016/j.ajog.2008.07.033].
Ammendola, M; Pietropolli, A; Lista, F; Saccucci, P; Piccione, E; Bottini, E; Gloria, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/17463
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