We have investigated the possible role of ACP1 (also known as cLMWPTP: cytosolic low molecular weight phosphotyrosine phosphatase), a highly polymorphic enzyme involved in signal transduction of T-cell receptor, insulin receptor and other growth factors in the relationship between maternal age at delivery and risk of type 1 diabetes in the offspring.
Bottini, N., Meloni, G., Lucarelli, P., Amante, A., Saccucci, P., Gloria, F., et al. (2004). Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex. DIABETES/METABOLISM RESEARCH AND REVIEWS, 21(4), 353-358 [10.1002/dmrr.521].
Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex
BOTTINI, NUNZIO;AMANTE, ADA;SACCUCCI, PATRIZIA;GLORIA, FULVIA;BOTTINI, EGIDIO
2004-12-01
Abstract
We have investigated the possible role of ACP1 (also known as cLMWPTP: cytosolic low molecular weight phosphotyrosine phosphatase), a highly polymorphic enzyme involved in signal transduction of T-cell receptor, insulin receptor and other growth factors in the relationship between maternal age at delivery and risk of type 1 diabetes in the offspring.File in questo prodotto:
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