Nanoscience and nanotechnology are developing rapidly, and the applications of nanoparticles (NPs) have been found in several fields. At present, NPs are widely used in traditional consumer and industrial products, however, the properties and safety of NPs are still unclear and there are concerns about their potential environmental and health effects. The aim of the present study was to investigate the potential toxicity of ZnO NPs on testicular cells using both in vitro and in vivo systems in a mouse experimental model.

Han, Z., Yan, Q., Ge, W., Liu, Z., Gurunathan, S., DE FELICI, M., et al. (2016). Cytotoxic effects of ZnO nanoparticles on mouse testicular cells. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 5187-5203 [10.2147/IJN.S111447].

Cytotoxic effects of ZnO nanoparticles on mouse testicular cells

DE FELICI, MASSIMO;
2016-01-01

Abstract

Nanoscience and nanotechnology are developing rapidly, and the applications of nanoparticles (NPs) have been found in several fields. At present, NPs are widely used in traditional consumer and industrial products, however, the properties and safety of NPs are still unclear and there are concerns about their potential environmental and health effects. The aim of the present study was to investigate the potential toxicity of ZnO NPs on testicular cells using both in vitro and in vivo systems in a mouse experimental model.
2016
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/17 - ISTOLOGIA
English
Leydig cells; Sertoli cells; ZnO nanoparticle; mice; Animals; Apoptosis; Cells, Cultured; DNA Damage; Humans; Leydig Cells; Male; Metal Nanoparticles; Mice; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanotechnology; Reactive Oxygen Species; Sertoli Cells; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction; Zinc Oxide
Han, Z., Yan, Q., Ge, W., Liu, Z., Gurunathan, S., DE FELICI, M., et al. (2016). Cytotoxic effects of ZnO nanoparticles on mouse testicular cells. INTERNATIONAL JOURNAL OF NANOMEDICINE, 11, 5187-5203 [10.2147/IJN.S111447].
Han, Z; Yan, Q; Ge, W; Liu, Z; Gurunathan, S; DE FELICI, M; Shen, W; Zhang, X
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/173577
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