The proportion of HCV-infected patients over age 65 years in Western countries is increasing. This growth and the advent of new antiviral therapy bring into the question the real-world efficacy and safety of the combination of sofosbuvir (SOF) and simeprevir (SMV) plus a flat dose of 800 mg/d ribavirin (RBV) in elderly patients with cirrhosis compared to younger patients.

Pellicelli, A., Pace Palitti, V., Vignally, P., CECCHERINI SILBERSTEIN, F., Siciliano, M., Giannelli, V., et al. (2017). Efficacy and safety of sofosbuvir/simeprevir plus flat dose ribavirin in genotype 1 elderly cirrhotic patients: A real-life study. LIVER INTERNATIONAL, 37(5), 653-661 [10.1111/liv.13288].

Efficacy and safety of sofosbuvir/simeprevir plus flat dose ribavirin in genotype 1 elderly cirrhotic patients: A real-life study

CECCHERINI SILBERSTEIN, FRANCESCA;MESSINA, VALERIA;IZZI, ALESSANDRO;D'AMBROSIO, CLAUDIO;SACCO, ROBERTO;PERNO, CARLO FEDERICO;
2017

Abstract

The proportion of HCV-infected patients over age 65 years in Western countries is increasing. This growth and the advent of new antiviral therapy bring into the question the real-world efficacy and safety of the combination of sofosbuvir (SOF) and simeprevir (SMV) plus a flat dose of 800 mg/d ribavirin (RBV) in elderly patients with cirrhosis compared to younger patients.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - Microbiologia e Microbiologia Clinica
English
Con Impact Factor ISI
cirrhosis; elderly; genotype 1; hepatitis C; simeprevir; sofosbuvir
Pellicelli, A., Pace Palitti, V., Vignally, P., CECCHERINI SILBERSTEIN, F., Siciliano, M., Giannelli, V., et al. (2017). Efficacy and safety of sofosbuvir/simeprevir plus flat dose ribavirin in genotype 1 elderly cirrhotic patients: A real-life study. LIVER INTERNATIONAL, 37(5), 653-661 [10.1111/liv.13288].
Pellicelli, A; Pace Palitti, V; Vignally, P; CECCHERINI SILBERSTEIN, F; Siciliano, M; Giannelli, V; Moretti, A; Tarquini, P; Scifo, G; Messina, V; Ascione, A; Izzi, A; Marignani, M; D'Ambrosio, C; Fondacaro, L; Ettorre, G; Ialongo, P; Sacco, R; Perno, Cf; Barbarini, G
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/173559
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 11
social impact