A lab-worker was infected with HIV-1 in a biosafety level-2 of containment, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone, unknowingly contaminating a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs.

Soria, A., Alteri, C., Scarlatti, G., Bertoli, A., Tolazzi, M., Balestra, E., et al. (2017). Occupational HIV infection in a research laboratory with unknown mode of transmission: a case report. CLINICAL INFECTIOUS DISEASES, 64(6), 3-15 [10.1093/cid/ciw851].

Occupational HIV infection in a research laboratory with unknown mode of transmission: a case report

ALTERI, CLAUDIA;BERTOLI, ADA;BALESTRA, EMANUELA;BELLOCCHI, MARIA CONCETTA;CECCHERINI SILBERSTEIN, FRANCESCA;PERNO, CARLO FEDERICO;
2017

Abstract

A lab-worker was infected with HIV-1 in a biosafety level-2 of containment, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone, unknowingly contaminating a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - Microbiologia e Microbiologia Clinica
English
HIV transmission; HIV-1; laboratory safety; occupational exposure
Soria, A., Alteri, C., Scarlatti, G., Bertoli, A., Tolazzi, M., Balestra, E., et al. (2017). Occupational HIV infection in a research laboratory with unknown mode of transmission: a case report. CLINICAL INFECTIOUS DISEASES, 64(6), 3-15 [10.1093/cid/ciw851].
Soria, A; Alteri, C; Scarlatti, G; Bertoli, A; Tolazzi, M; Balestra, E; Bellocchi, Mc; Continenza, F; Carioti, L; Biasin, M; Trabattoni, D; Bandera, A; CECCHERINI SILBERSTEIN, F; Perno, Cf; Gori, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/173213
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