An impaired HBsAg-secretion can increase HBV oncogenic-properties. Here, we investigate genetic-determinants in HBsAg correlated with HBV-induced hepatocellular carcinoma (HCC), and their impact on HBsAg-secretion and cell-proliferation.
Salpini, R., Surdo, M., Warner, N., Cortese, M.f., Colledge, D., Soppe, S., et al. (2017). Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro. ONCOTARGET, 8(9), 15704-15715 [10.18632/oncotarget.14944].
Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro
SALPINI, ROMINA;SURDO, MATTEO;CORTESE, MARIA FRANCESCA;BELLOCCHI, MARIA CONCETTA;ARMENIA, DANIELE;SACCOMANDI, PATRIZIA;POLLICITA, MICHELA;BERTOLI, ADA;SARRECCHIA, CESARE;ORECCHINI, ELISA;MICHIENZI, ALESSANDRO;ANDREONI, MASSIMO;FRANCIOSO, SIMONA;ANGELICO, MARIO;CECCHERINI SILBERSTEIN, FRANCESCA;PERNO, CARLO FEDERICO;SVICHER, VALENTINA
2017-02-01
Abstract
An impaired HBsAg-secretion can increase HBV oncogenic-properties. Here, we investigate genetic-determinants in HBsAg correlated with HBV-induced hepatocellular carcinoma (HCC), and their impact on HBsAg-secretion and cell-proliferation.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
oncotarget-08-15704.pdf
solo utenti autorizzati
Licenza:
Non specificato
Dimensione
1.9 MB
Formato
Adobe PDF
|
1.9 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
