In the past 20 years, research and clinical trials on the healing process of chronic wounds have highlighted the key role of the family of enzymes called matrix metalloproteinases (MMPs). If a strong correlation between the course of healing of chronic wounds and the levels of a biological marker can be demonstrated, then it may be possible to: i) identify the best marker threshold to predict the clinical evolution of the pathology; and ii) if causality has been found between the marker and pathology, to improve the healing outcome, to change the marker level.

Lazaro, J., Izzo, V., Meaume, S., Davies, A., Lobmann, R., Uccioli, L. (2016). Elevated levels of matrix metalloproteinases and chronic wound healing: An updated review of clinical evidence. JOURNAL OF WOUND CARE, 25(5), 277-287 [10.12968/jowc.2016.25.5.277].

Elevated levels of matrix metalloproteinases and chronic wound healing: An updated review of clinical evidence

UCCIOLI, LUIGI
2016

Abstract

In the past 20 years, research and clinical trials on the healing process of chronic wounds have highlighted the key role of the family of enzymes called matrix metalloproteinases (MMPs). If a strong correlation between the course of healing of chronic wounds and the levels of a biological marker can be demonstrated, then it may be possible to: i) identify the best marker threshold to predict the clinical evolution of the pathology; and ii) if causality has been found between the marker and pathology, to improve the healing outcome, to change the marker level.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/13 - Endocrinologia
English
Con Impact Factor ISI
chronic wound; matrix metalloproteinase; wound healing; Acute Disease; Chronic Disease; Humans; Individuality; Matrix Metalloproteinases; Prognosis; Wounds and Injuries; Wound Healing
Lazaro, J., Izzo, V., Meaume, S., Davies, A., Lobmann, R., Uccioli, L. (2016). Elevated levels of matrix metalloproteinases and chronic wound healing: An updated review of clinical evidence. JOURNAL OF WOUND CARE, 25(5), 277-287 [10.12968/jowc.2016.25.5.277].
Lazaro, J; Izzo, V; Meaume, S; Davies, A; Lobmann, R; Uccioli, L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/171308
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