HIV genetic diversity implicates major challenges for the control of viral infection by the immune system and for the identification of an effective immunotherapeutic strategy. With the present case report we underline as HIV evolution could be effectively halted by early antiretroviral treatment (eART). Few cases supported this evidence due to the difficulty of performing amplification and sequencing analysis in long-term viral suppressed patients. Here, we reported the case of limited HIV-1 viral evolution over time in a successful early treated child.

Palma, P., Zangari, P., Alteri, C., Tchidjou, H., Manno, E., Liuzzi, G., et al. (2016). Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child. BMC INFECTIOUS DISEASES, 16(1), 742 [10.1186/s12879-016-2092-z].

Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child

Palma, P;ALTERI, CLAUDIA;PERNO, CARLO FEDERICO;ROSSI, PAOLO;BERTOLI, ADA;
2016-01-01

Abstract

HIV genetic diversity implicates major challenges for the control of viral infection by the immune system and for the identification of an effective immunotherapeutic strategy. With the present case report we underline as HIV evolution could be effectively halted by early antiretroviral treatment (eART). Few cases supported this evidence due to the difficulty of performing amplification and sequencing analysis in long-term viral suppressed patients. Here, we reported the case of limited HIV-1 viral evolution over time in a successful early treated child.
2016
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Children; Early antiretroviral treatment; HIV; Immunotherapy; Viral evolution
Palma, P., Zangari, P., Alteri, C., Tchidjou, H., Manno, E., Liuzzi, G., et al. (2016). Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child. BMC INFECTIOUS DISEASES, 16(1), 742 [10.1186/s12879-016-2092-z].
Palma, P; Zangari, P; Alteri, C; Tchidjou, H; Manno, E; Liuzzi, G; Perno, Cf; Rossi, P; Bertoli, A; Bernardi, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/171267
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