HIV genetic diversity implicates major challenges for the control of viral infection by the immune system and for the identification of an effective immunotherapeutic strategy. With the present case report we underline as HIV evolution could be effectively halted by early antiretroviral treatment (eART). Few cases supported this evidence due to the difficulty of performing amplification and sequencing analysis in long-term viral suppressed patients. Here, we reported the case of limited HIV-1 viral evolution over time in a successful early treated child.
Palma, P., Zangari, P., Alteri, C., Tchidjou, H., Manno, E., Liuzzi, G., et al. (2016). Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child. BMC INFECTIOUS DISEASES, 16(1), 742 [10.1186/s12879-016-2092-z].
Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child
Palma, P;ALTERI, CLAUDIA;PERNO, CARLO FEDERICO;ROSSI, PAOLO;BERTOLI, ADA;
2016-01-01
Abstract
HIV genetic diversity implicates major challenges for the control of viral infection by the immune system and for the identification of an effective immunotherapeutic strategy. With the present case report we underline as HIV evolution could be effectively halted by early antiretroviral treatment (eART). Few cases supported this evidence due to the difficulty of performing amplification and sequencing analysis in long-term viral suppressed patients. Here, we reported the case of limited HIV-1 viral evolution over time in a successful early treated child.File | Dimensione | Formato | |
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2016_Early antiretroviral treatment eART limits viral diversity over time in a long term HIV viral suppressed perinatally infected child.pdf
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