Amplification of the epidermal growth factor receptor (EGFR) and its mutant EGFRvIII are among the most common genetic alterations in glioblastoma (GBM), the most frequent and most aggressive primary brain tumor.
Eskilsson, E., Rosland, G., Talasila, K., Knappskog, S., Keunen, O., Sottoriva, A., et al. (2016). EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation. NEURO-ONCOLOGY, 18(12), 1-12 [10.1093/neuonc/now113].
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation
GRAZIANI, GRAZIA;
2016-01-01
Abstract
Amplification of the epidermal growth factor receptor (EGFR) and its mutant EGFRvIII are among the most common genetic alterations in glioblastoma (GBM), the most frequent and most aggressive primary brain tumor.File in questo prodotto:
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