Patients with Scans-Without-Evidence-of-Dopaminergic-Deficit (SWEDD) often present asymmetric rest tremor not responsive to levodopa. Although a dystonic origin of this tremor has been proposed, the underlying pathophysiology of such condition is still unclear. An abnormal activity in the Cerebello-Thalamo-Cortical circuit is involved in the pathogenesis of tremor and other movement disorders. Here we used different paradigms of cerebellar transcranial magnetic stimulation to evaluate the Cerebello-Thalamo-Cortical functioning in patients with normal scans.

Schirinzi, T., Di Lorenzo, F., Ponzo, V., Palmieri, M., Bentivoglio, A., Schillaci, O., et al. (2016). Mild cerebello-thalamo-cortical impairment in patients with normal dopaminergic scans (SWEDD). PARKINSONISM & RELATED DISORDERS, 28, 23-28 [10.1016/j.parkreldis.2016.03.023].

Mild cerebello-thalamo-cortical impairment in patients with normal dopaminergic scans (SWEDD)

SCHIRINZI, TOMMASO;SCHILLACI, ORAZIO;PISANI, ANTONIO;
2016

Abstract

Patients with Scans-Without-Evidence-of-Dopaminergic-Deficit (SWEDD) often present asymmetric rest tremor not responsive to levodopa. Although a dystonic origin of this tremor has been proposed, the underlying pathophysiology of such condition is still unclear. An abnormal activity in the Cerebello-Thalamo-Cortical circuit is involved in the pathogenesis of tremor and other movement disorders. Here we used different paradigms of cerebellar transcranial magnetic stimulation to evaluate the Cerebello-Thalamo-Cortical functioning in patients with normal scans.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26 - Neurologia
English
Con Impact Factor ISI
Cerebello thalamo cortical; Dystonia; Parkinson's disease; SWEDD; Tremor
https://www.sciencedirect.com/science/article/pii/S1353802016300773?via%3Dihub
Schirinzi, T., Di Lorenzo, F., Ponzo, V., Palmieri, M., Bentivoglio, A., Schillaci, O., et al. (2016). Mild cerebello-thalamo-cortical impairment in patients with normal dopaminergic scans (SWEDD). PARKINSONISM & RELATED DISORDERS, 28, 23-28 [10.1016/j.parkreldis.2016.03.023].
Schirinzi, T; Di Lorenzo, F; Ponzo, V; Palmieri, M; Bentivoglio, A; Schillaci, O; Pisani, A; Koch, G
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/168943
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