In airway infections, biofilm formation has been demonstrated to be responsible for both acute and chronic events, and constitutes a genuine challenge in clinical practice. Difficulty in eradicating biofilms with systemic antibiotics has led clinicians to consider the possible role of non-antibiotic therapy. The aim of this review is to examine current evidence for the use of N-acetylcysteine (NAC) in the treatment of biofilm-related respiratory infections.

Blasi, F., Page, C., Rossolini, G., Pallecchi, L., Matera, M., Rogliani, P., et al. (2016). The effect of N-acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections. RESPIRATORY MEDICINE, 117, 190-197 [10.1016/j.rmed.2016.06.015].

The effect of N-acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections

ROGLIANI, PAOLA;CAZZOLA, MARIO
2016-01-01

Abstract

In airway infections, biofilm formation has been demonstrated to be responsible for both acute and chronic events, and constitutes a genuine challenge in clinical practice. Difficulty in eradicating biofilms with systemic antibiotics has led clinicians to consider the possible role of non-antibiotic therapy. The aim of this review is to examine current evidence for the use of N-acetylcysteine (NAC) in the treatment of biofilm-related respiratory infections.
2016
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/10 - MALATTIE DELL'APPARATO RESPIRATORIO
English
Airways infections; Biofilm; Inhaled formulation; N-acetylcysteine; Topical administration
Blasi, F., Page, C., Rossolini, G., Pallecchi, L., Matera, M., Rogliani, P., et al. (2016). The effect of N-acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections. RESPIRATORY MEDICINE, 117, 190-197 [10.1016/j.rmed.2016.06.015].
Blasi, F; Page, C; Rossolini, G; Pallecchi, L; Matera, M; Rogliani, P; Cazzola, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/166407
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