The prevalence of idiopathic pulmonary fibrosis (IPF) is increasing every year. Pirfenidone and nintedanib were approved for treatment of IPF in 2014, but they received only a conditional recommendation for use and, thus, to date no drugs are strongly recommended for IPF. The aim of this study was to assess the effectiveness and safety of the currently approved drugs for IPF and N-acetylcysteine (NAC), the most debated drug in the last update of guidelines for IPF treatment.

Rogliani, P., Calzetta, L., Cavalli, F., Matera, M., Cazzola, M. (2016). Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis. PULMONARY PHARMACOLOGY & THERAPEUTICS, 40, 95-103 [10.1016/j.pupt.2016.07.009].

Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis

ROGLIANI, PAOLA;CAZZOLA, MARIO
2016-01-01

Abstract

The prevalence of idiopathic pulmonary fibrosis (IPF) is increasing every year. Pirfenidone and nintedanib were approved for treatment of IPF in 2014, but they received only a conditional recommendation for use and, thus, to date no drugs are strongly recommended for IPF. The aim of this study was to assess the effectiveness and safety of the currently approved drugs for IPF and N-acetylcysteine (NAC), the most debated drug in the last update of guidelines for IPF treatment.
2016
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/10 - MALATTIE DELL'APPARATO RESPIRATORIO
English
Con Impact Factor ISI
IPF; Meta-analysis; Therapy
http://www.sciencedirect.com/science/article/pii/S109455391630061X
Rogliani, P., Calzetta, L., Cavalli, F., Matera, M., Cazzola, M. (2016). Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis. PULMONARY PHARMACOLOGY & THERAPEUTICS, 40, 95-103 [10.1016/j.pupt.2016.07.009].
Rogliani, P; Calzetta, L; Cavalli, F; Matera, M; Cazzola, M
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S109455391630061X-main.pdf

solo utenti autorizzati

Tipologia: Versione Editoriale (PDF)
Licenza: Non specificato
Dimensione 744.07 kB
Formato Adobe PDF
744.07 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/164047
Citazioni
  • ???jsp.display-item.citation.pmc??? 49
  • Scopus 110
  • ???jsp.display-item.citation.isi??? 102
social impact