To compare single-agent gemtuzumab ozogamicin (GO) with best supportive care (BSC) including hydroxyurea as first-line therapy in older patients with acute myeloid leukemia unsuitable for intensive chemotherapy.

Amadori, S., Suciu, S., Selleslag, D., Aversa, F., Gaidano, G., Musso, M., et al. (2016). Gemtuzumab Ozogamicin Versus Best Supportive Care in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Unsuitable for Intensive Chemotherapy: Results of the Randomized Phase III EORTC-GIMEMA AML-19 Trial. JOURNAL OF CLINICAL ONCOLOGY, 34(9), 972-979 [10.1200/JCO.2015.64.0060].

Gemtuzumab Ozogamicin Versus Best Supportive Care in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Unsuitable for Intensive Chemotherapy: Results of the Randomized Phase III EORTC-GIMEMA AML-19 Trial

AMADORI, SERGIO;VENDITTI, ADRIANO;VOSO, MARIA TERESA;MAZZONE, CARLA;DE FABRITIIS, PAOLO;MANCINI, MARCO;
2016-03-20

Abstract

To compare single-agent gemtuzumab ozogamicin (GO) with best supportive care (BSC) including hydroxyurea as first-line therapy in older patients with acute myeloid leukemia unsuitable for intensive chemotherapy.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - Malattie del Sangue
English
Age Factors; Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged
Amadori, S., Suciu, S., Selleslag, D., Aversa, F., Gaidano, G., Musso, M., et al. (2016). Gemtuzumab Ozogamicin Versus Best Supportive Care in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Unsuitable for Intensive Chemotherapy: Results of the Randomized Phase III EORTC-GIMEMA AML-19 Trial. JOURNAL OF CLINICAL ONCOLOGY, 34(9), 972-979 [10.1200/JCO.2015.64.0060].
Amadori, S; Suciu, S; Selleslag, D; Aversa, F; Gaidano, G; Musso, M; Annino, L; Venditti, A; Voso, Mt; Mazzone, C; Magro, D; DE FABRITIIS, P; Muus, P; Alimena, G; Mancini, M; Hagemeijer, A; Paoloni, F; Vignetti, M; Fazi, P; Meert, L; Ramadan, S; Willemze, R; de Witte, T; Baron, F
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/162799
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